Baker Street Irregular

A treatise on this written at the age of 21 had a European vogue and earned its author a professorship (8,7)

It was of course to see these that Holmes enquired the way from Saxe-Coburg Square to the Strand (10,5)

How the pips were set (2)

Not an Eley's No. 2 (which is an excellent argument with a gentleman who can twist steel pokers into knots) but the weapon in the the tragedy of Birlstone (3)

What was done on the opposite wall in bullet-pocks by the patriotic Holmes (2)

What Watson recognized when he put his hand on Bartholomew Sholto's leg (5)

Where Watson met young Stamford, who introduced him to Sherlock Holmes (3)

A kind of pet, over which Dr. Grimesby Roylott hurled the local blacksmith (4)

Holmes should have said this before being so sure of catching the murderers of John Openshaw (2)

The kind of Pedro whence came the tiger (3)

Though he knew the methods, Watson sometimes found it difficult to do this (3)

Patron saint of old Mr. Ferguson's affliction and perhaps of Abe Slaney's men (5)

Perhaps a measure of Holmes's chemicals (2)

In short, Watson (2)

(2)

Curious that he did nothing in the nighttime (3)

This would obviously not describe the empty house across from 221b Baker Street (3)

It seems likely that Watson's older brother suffered from this disease (2)

Though you might have taken this at Lodge 29, Chicago, nevertheless you had to pass a test as well at Lodge 341, Vermissa (4)

The Star of Savannah (4)

Mrs. Barclay's reproach (in The Crooked Man, of course) suggests the parable of this (3)

Scrawled in blood-red letters across the bare plaster at No. 3, Lauriston Gardens (5)

Holmes found this because he was looking for it in the mud (5)

Suggests Jonathan Small's leg (3)

The brother who left Watson no choice but to relate the Final Problem (5,8)

A country district in the West of England where 'Cooee' was a common signal (8,6)

Charles Augustus Milverton dealt with no niggard hand; therefore this would not describe him (4)

The kind of practice indulged by Mr. Williamson, the solitary cyclist's unfrocked clergyman -- "there was a man of that name in orders, whose career has been a singularly dark one." (3)

There is comparatively as much sense in Hafiz. Indeed, it's a case of identity. (2,2,6)

Caused the rift in the Beryl Coronet (3)

Many of Holmes's opponents had cause to (3)

Begins: 'Whose was it?' 'His who has gone.' 'Who shall have it?' 'He who will come.' (8,6)

of four (4)

The number of Napeoleons plus the number of the Randall gang (4)

One of the five sent 'S.H. for J.O.' (3)

To save the dying detective trouble, Mr. Culverton Smith was kind enough to give the signal by turning this up (3)

The blundering constable who failed to gain his sergeant's stripes in the Lauriston Garden Mystery (5)

There was a giant one of Sumatra; yet it was unwritten (3)

How Watson felt after the Final Problem (3)

He was epollicate (8)

Initials of the second most dangerous man in London (2)

Though Miss Mary Sutherland's boots were not unlike, they were really odd ones; the one having this slightly decorated, and the other plain (3)

You may forgive the plural form of these tobaccos, since Holmes smoked so much of them (5)

Behind this Black Jack of Ballarat waited and smoked an Indian cigar, of the variety which are rolled in Rotterdam (4)

(+ 39 Down) The best I can make of these is the Latin for the sufferers of the epidemic which pleased Holmes so extremely that he said 'A long shot, Watson, a very long shot,' and pinched the Doctor's arm (4)

See 38 Down

One of the two in the cardboard box (3)

Initials of the street in which Mycroft lodged (2)